Blood Clotting Essay

Coagulation, or thrombogenesis, is the process by which furrow change states in an move to restrict product line loss from an injury site, and repair the damaged vessel. just about of the time coagulation is a good thing, however there argon circumstances when a choke can form abnormally, leading to nubble attack, stroke, or otherwise earnest medical problems. A line of descent clot forms almost immediately after the bleeding occurs, which is possible through enzymes and other substances in blood that respond to breaks in vessel hem ins.The clot is a temporary fix preventing further blood loss. There argon quaternion major parts of blood clot formation. The first step in clotting is the formation of the platelet hacker. Platelets are the smallest of the three major types of blood cells whose primary function is to prevent bleeding. When encountering a damaged blood vessel, the platelets run short stimulated and rush to the injury site where they clump together, forming a plug and restricting the bleeding. They alike release substances to begin the chemical reaction of the clotting process.These chemical reactions are responsible for growing the blood clot. Dissolved proteins, also referred to as clotting factors, are contained within the blood for the purpose of promoting blood clots. These proteins send signals to each other and enhance each others activity exponentially at the site of injury, resulting in a quick chemical chain reaction which produces fibrin, the main protein forming clots. This blood clot make with fibrin is tougher and more durable than the platelet plug.Once the blood clot forms, it is alpha that it non grow and spread to the rest of the body, which can cause serious damage. This is where anti-clotting grows in to play. Proteins such as antithrombin, protein C, and protein S, are known anti-clotting proteins and exist in a natural balance with the clotting factors. These substances work to neutralize superabundance clo tting factors, preventing the clot from going to places it should not. The final part of the process is where the clot is slowly broken down by the body. Once the damaged create from raw material heals, the body gradually degrades the clot and reabsorbs it.The tough fibrin strands in a blood clot are dissolved by an enzyme called plasmin. Plasmin is activated by other substances working together to help the clot break down. The totally process of blood clotting is whenever the blood is exposed to certain substances. These are known as thrombogenic substances because they promotethe formation of thrombus (clot). Many of these substances, such as tissue factor, collagen, and von Willebrand factor, are located in the skin or in the blood vessel walls, typically separated from flowing blood.If they come into contact with flowing blood, this typically means the blood vessel wall is ruptured and bleeding. A clot may also form when blood is not flowing properly. http//www.hematology.org/ patients/blood-disorders/blood-clots/5233.aspx http//www.webmd.com/a-to-z-guides/blood-clots